Chlorhexidine digluconate Mouthwash For Anti Plaque And Fungal

Chlorhexidine digluconate mouthwash uses, side effects, diseases that it cures like plaque, fungal,acute leukemia, gingivitis and Case studies by Oxford, NCBI and Scielo and list of mouthwashes.

Chlorhexidine digluconate Mouthwash For Anti Plaque And Fungal

In this researched post we are going to discuss chlorhexidine gluconate mouthwash on following topics.

1. Chlorhexidine digluconate
2. Chlorhexidine digluconate Uses
3. Chlorhexidine digluconate side effects
4. Diseases that Chlorhexidine digluconate mouthwash can cure
5. NCBI case study that proves Chlorhexidine digluconate reduces the level of bacteria
6. Oxford case study that proves Chlorhexidine digluconate is better than povidone iodine
7. Scielo case study that proves Chlorhexidine digluconate helps to treat acute leukemia
8. List of mouthwash that contains Chlorhexidine digluconate

Chlorhexidine Gluconate 

1. Class: Local Anti-infectives, Miscellaneous
2. Chemical Name: N,N′′-Bis(4-chlorophenyl)-3,12-diimino- 2,4,11,13-tetraazatetradecanediimidamide di-d-gluconate
3. Molecular Formula: C22H30Cl2N10•2C6H12O7

Chlorhexidine gluconate Uses

Chlorhexidine gluconate is used in mouthwash, toothpaste. cosmetic items, deodorants and antiperspirants. Also used in disinfection of the skin and hands. Along with it is also used in pharmaceutical products (preservative in eye drops, active substance in wound dressings and antiseptic mouthwashes).

1. Chlorhexidine digluconate is a chemical antiseptic and is used in a 0.12-0.2% solution as a mouthwash. 
2. Works as anti-plaque and anti fungal in mouthwashes.
3. It is very effective in Gram-negative rods.
4. Rinsing with chlorhexidine mouthwash before a tooth extraction reduces the risk of dry socket, a painful condition where the blood clot is lost from an extraction socket and bone is exposed to the oral cavity.

Side Effects of Chlorhexidine gluconate

1. Blistering, burning, itching, peeling, skin rash, redness, swelling, or other signs of irritation on the skin.
2. Swelling of the face, hands, or feet.
3. Trouble breathing.

Chlorhexidine gluconate is used to cure for following diseases

Cetylpyridinium gluconate mouthwash are used for following types of diseases which reduces your oral hygiene are listed below.

Chlorhexidine gluconate is used as an active ingredient in mouthwash because that reduces dental plaque and oral bacteria. Chlorhexidine lasts longer in mouth than the other mouthwash and that is why it is more preferred in curing gingitivits. So use of chlorhexidine gluconate mouthwash cure thee types of diseases :-

• Dental Plaque
• Oral Bacteria
• Gingitivitis

Who should not use chlorhexidine gluconate mouthwash

Chlorhexidine gluconate mouthwash or oral rinse reduces the level of bacteria.

This case study conducted by National Center for Biotechnology Information shows that use of Chlorhexidine gluconate helped in decreasing the level of bacteria and reduce the prevalence of nosocomial pneumonia in patients who were going through heart surgery.

"The overall rate of nosocomial pneumonia was reduced by 52% (4/270 vs 9/291; P = .21) in the Peridex-treated patients. Among patients intubated for more than 24 hours who had cultures that showed microbial growth (all pneumonias occurred in this group), the pneumonia rate was reduced by 58% (4/19 vs 9/18; P = .06) in patients treated with Peridex. In patients at highest risk for pneumonia (intubated > 24 hours, with cultures showing the most growth), the rate was 71% lower in the Peridex group than in the Listerine group (2/10 vs 7/10; P = .02)."

Oxfordjournal compares the chlorhexidine gluconate with povidone iodine and finds shocking results.

They shared clinical and economical benefits of using chlorhexidine gluconate with povidone iodine and shared these results. You can read the full case study here.

"The use of chlorhexidine gluconate solution for vascular catheter insertion site care reduces the risk of catheter-related bloodstream infection by one-half, compared with povidone iodine. Our objective was to evaluate the cost-effectiveness of chlorhexidine gluconate versus povidone iodine. We used data from randomized, controlled trials, meta-analyses, and epidemiologic studies to construct a decision analysis model. We estimated that use of chlorhexidine, rather than povidone, for central catheter site care resulted in a 1.6% decrease in the incidence of catheter-related bloodstream infection, a 0.23% decrease in the incidence of death, and savings of $113 per catheter used. For peripheral catheter site care, the results were similar, although the differences were smaller. The results were found to be robust on multivariate sensitivity analyses. Use of chlorhexidine gluconate in place of the current standard solution for vascular catheter site care is a simple and cost-effective method of improving patient safety in the hospital setting."

Scielo shares the importance of chlorhexidine gluconate

They describe that use of chlorhexidine gluconate is able to decrease the frequency and intensity of oral mucosa injuries without significant noxious effects. And it also helps to treat acute leukemia.

You must read this case study at here.

"Leukemias impair hematopoietic stem-cells shunting and promote a proliferation of malignant cells without functional competence. Studies point that oral manifestations such as pain, hyperplasia and gum bleeding may be one of the first signs in leukemia patients. In light of the above, this study aimed at carrying out a systematic analysis of articles published in the last 15 years, with regard to chlorhexidine to treat and prevent mucositis in acute leukemia children under chemotherapy.Chlorhexidine gluconate does not totally eliminate oral mucosa injuries, but is able to decrease their frequency and intensity without significant noxious effects. However, other drugs compared to chlorhexidine in this study may present better results."

So Chlorhexidine gluconate mouthwash are able to control plaque and fungal along with helps to decrease the bacteria present in your mouth without noxious effects. Below we are sharing a list of mouthwash that contains chlorhexidine gluconate.

List of mouthwash that contains chlorhexidine gluconate

Corsodyl mint mouthwash
Care plus chlorhexidine digluconate antiseptic mouthwash
BDSI Limited Chlorhexidine Antiseptic mouthwash